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Merck

RPS6KB1

ribosomal protein S6 kinase, 70kDa, polypeptide 1

Synonyms:
PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70 S6KA, p70(S6K)-alpha, p70-S6K, p70-alpha
Species:
Human RPS6KB1 (6198), Mouse Rps6kb1 (72508), Rat Rps6kb1 (83840), chicken RPS6KB1 (417637), domestic cat RPS6KB1 (101092561), Horse RPS6KB1 (100057481), dog RPS6KB1 (480580), cow RPS6KB1 (404181), sheep RPS6KB1 (101107371), domestic guinea pig Rps6kb1 (100727216) ...More
UniProtKB ID:
P23443
Gene ID:
  • Human(6198) Summary: This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013]
  • Mouse(72508) ribosomal protein S6 kinase, polypeptide 1
  • Rat(83840) ribosomal protein S6 kinase, polypeptide 1
  • chicken(417637) ribosomal protein S6 kinase, 70kDa, polypeptide 1
  • domestic cat(101092561) ribosomal protein S6 kinase, 70kDa, polypeptide 1
  • Horse(100057481) ribosomal protein S6 kinase, 70kDa, polypeptide 1
  • dog(480580) ribosomal protein S6 kinase, 70kDa, polypeptide 1
  • cow(404181) ribosomal protein S6 kinase, 70kDa, polypeptide 1
  • sheep(101107371) ribosomal protein S6 kinase, 70kDa, polypeptide 1
  • domestic guinea pig(100727216) ribosomal protein S6 kinase, 70kDa, polypeptide 1
  • naked mole-rat(101724077) ribosomal protein S6 kinase, 70kDa, polypeptide 1
  • Domestic Rabbit(100009260) ribosomal protein S6 kinase, 70kDa, polypeptide 1

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Antibodies

Product Number
Description
Species Reactivity
Application
07-402
Anti-p70 S6 Kinase Antibody, Upstate®, from rabbit,
Species Reactivity
human, mouse, rat
Application
immunoprecipitation (IP)
western blot