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Merck

RNF2

ring finger protein 2

Synonyms:
BAP-1, BAP1, DING, HIPI3, RING1B, RING2
Species:
UniProtKB ID:
Gene ID:
  • Human(6045) Summary: Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity. [provided by RefSeq, Jul 2008]
  • Mouse(19821) ring finger protein 2
  • Rat(304850) ring finger protein 2
  • Zebrafish(327035) ring finger protein 2
  • chicken(424452) ring finger protein 2
  • domestic cat(101086442) ring finger protein 2
  • dog(480042) ring finger protein 2
  • domestic guinea pig(100717673) ring finger protein 2
  • Domestic Rabbit(100344273) ring finger protein 2
  • naked mole-rat(101708386) ring finger protein 2
  • cow(540090) ring finger protein 2
  • sheep(101108242) ring finger protein 2

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