RET
ret proto-oncogene
Synonyms:
CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET-ELE1, RET51
Species:
Human RET (5979), Mouse Ret (19713), Rat Ret (24716), fruit fly ret (44319), fruit fly Ret (43875), Horse RET (100033966), domestic cat RET (101101086), dog RET (403494), chicken RET (396107), Zebrafish ret (30512) ...More
UniProtKB ID:
Gene ID:
- Human(5979) Summary: This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. [provided by RefSeq, Jul 2008]
- Mouse(19713) ret proto-oncogene
- Rat(24716) ret proto-oncogene
- fruit fly(44319) reticulated
- fruit fly(43875) Ret oncogene
- Horse(100033966) ret proto-oncogene
- domestic cat(101101086) ret proto-oncogene
- dog(403494) ret proto-oncogene
- chicken(396107) ret proto-oncogene
- Zebrafish(30512) ret proto-oncogene receptor tyrosine kinase
- domestic guinea pig(100733392) ret proto-oncogene
- Domestic Rabbit(100340710) ret proto-oncogene
- naked mole-rat(101717565) ret proto-oncogene
- cow(515924) ret proto-oncogene
- sheep(101119787) ret proto-oncogene
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Proteins
Product Number
Description
Species
Ret Protein, active, 10 µg, Active, N-Terminal GST-tagged, recombinant, human Ret amino acids 658-end, for use in Kinase Assays.,
Species
human