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Merck

RAB7A

RAB7A, member RAS oncogene family

Synonyms:
PRO2706, RAB7
Species:
Human RAB7A (7879), Rat Rab7a (29448), cow RAB7A (509970), sheep RAB7A (100145880), Domestic Rabbit RAB7A (100008682), domestic guinea pig Rab7a (100721839), Thale Cress RAB7A (816724), chicken RAB7A (416016), dog RAB7A (404007)
UniProtKB ID:
P51149, A8K3V6, Q9NWJ0, Q9UPB0
Gene ID:
  • Human(7879) Summary: RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies. [provided by RefSeq, Jul 2008]
  • Rat(29448) RAB7A, member RAS oncogene family
  • cow(509970) RAB7A, member RAS oncogene family
  • sheep(100145880) RAB7A, member RAS oncogene family
  • Domestic Rabbit(100008682) RAB7A, member RAS oncogene family
  • domestic guinea pig(100721839) RAB7A, member RAS oncogene family
  • Thale Cress(816724) RAB GTPase-like protein 7A
  • chicken(416016) RAB7A, member RAS oncogene family
  • dog(404007) RAB7A, member RAS oncogene family

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