QDPR
quinoid dihydropteridine reductase
Synonyms:
DHPR, PKU2, SDR33C1
Species:
Human QDPR (5860), Mouse Qdpr (110391), Rat Qdpr (64192), cow QDPR (618084), sheep QDPR (101116833), domestic guinea pig Qdpr (100727648), naked mole-rat Qdpr (101712596), chicken QDPR (426335), domestic cat QDPR (101087576), dog QDPR (479082)
UniProtKB ID:
Gene ID:
- Human(5860) Summary: This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase. [provided by RefSeq, Jul 2008]
- Mouse(110391) quinoid dihydropteridine reductase
- Rat(64192) quinoid dihydropteridine reductase
- cow(618084) quinoid dihydropteridine reductase
- sheep(101116833) quinoid dihydropteridine reductase
- domestic guinea pig(100727648) quinoid dihydropteridine reductase
- naked mole-rat(101712596) quinoid dihydropteridine reductase
- chicken(426335) quinoid dihydropteridine reductase
- domestic cat(101087576) quinoid dihydropteridine reductase
- dog(479082) quinoid dihydropteridine reductase
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