Skip to Content
Merck

PTF1A

pancreas specific transcription factor, 1a

Synonyms:
PTF1-p48, bHLHa29
Species:
Human PTF1A (256297), Mouse Ptf1a (19213), Rat Ptf1a (117034), Zebrafish ptf1a (368662), dog PTF1A (608313), cow PTF1A (781540), naked mole-rat Ptf1a (101703535)
UniProtKB ID:
Q7RTS3, Q9HC25
Gene ID:
  • Human(256297) Summary: This gene encodes a protein that is a component of the pancreas transcription factor 1 complex (PTF1) and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. The protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase. Mutations in this gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers. [provided by RefSeq, Jul 2008]
  • Mouse(19213) pancreas specific transcription factor, 1a
  • Rat(117034) pancreas specific transcription factor, 1a
  • Zebrafish(368662) pancreas specific transcription factor, 1a
  • dog(608313) pancreas specific transcription factor, 1a
  • cow(781540) pancreas specific transcription factor, 1a
  • naked mole-rat(101703535) pancreas specific transcription factor, 1a

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.