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Merck

PSMD11

proteasome (prosome, macropain) 26S subunit, non-ATPase, 11

Synonyms:
Rpn6, S9, p44.5
Species:
Human PSMD11 (5717), Mouse Psmd11 (69077), Rat Psmd11 (303353), chicken PSMD11 (430878), domestic cat PSMD11 (101091665), dog PSMD11 (480610), cow PSMD11 (513461), sheep PSMD11 (101121105), naked mole-rat Psmd11 (101724437), domestic guinea pig Psmd11 (100718311)
UniProtKB ID:
O00231, A8K3I7, E1P663, O00495, Q53FT5
Gene ID:
  • Human(5717) Summary: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S9 family that functions as a non-ATPase subunit of the 19S regulator and is phosphorylated by AMP-activated protein kinase. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012]
  • Mouse(69077) proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
  • Rat(303353) proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
  • chicken(430878) proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
  • domestic cat(101091665) proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
  • dog(480610) proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
  • cow(513461) proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
  • sheep(101121105) proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
  • naked mole-rat(101724437) proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
  • domestic guinea pig(100718311) proteasome (prosome, macropain) 26S subunit, non-ATPase, 11

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