POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
Synonyms:
POLR2, POLRA, RPB1, RPBh1, RPO2, RPOL2, RpIILS, hRPB220, hsRPB1
Species:
Human POLR2A (5430), Mouse Polr2a (20020), Rat Polr2a (363633), domestic guinea pig Polr2a (100734232), naked mole-rat Polr2a (101725588), cow POLR2A (282312), sheep POLR2A (100144762), Zebrafish polr2a (553347), dog POLR2A (479483), domestic cat POLR2A (101098500)
UniProtKB ID:
Gene ID:
- Human(5430) Summary: This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008]
- Mouse(20020) polymerase (RNA) II (DNA directed) polypeptide A
- Rat(363633) polymerase (RNA) II (DNA directed) polypeptide A
- domestic guinea pig(100734232) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
- naked mole-rat(101725588) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
- cow(282312) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
- sheep(100144762) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
- Zebrafish(553347) polymerase (RNA) II (DNA directed) polypeptide A
- dog(479483) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
- domestic cat(101098500) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-RNA Polymerase II Antibody, clone ARNA-3, ascites fluid, clone ARNA-3, Chemicon®,
Species Reactivity
drosophila, human, kangaroo
Application
immunohistochemistry
western blot
western blot
Anti-RNA polymerase II Antibody, clone CTD4H8, clone CTD4H8, Upstate®, from mouse,
Species Reactivity
saccharomyces cerevisiae, human, mouse, rat
Application
ChIP
western blot
western blot