PKLR
pyruvate kinase, liver and RBC
Synonyms:
PK1, PKL, PKR, PKRL, RPK
Species:
Human PKLR (5313), Mouse Pklr (18770), Rat Pklr (24651), Zebrafish pklr (114551), domestic cat PKLR (100750244), domestic cat PKLR (101088459), dog PKLR (490425), domestic guinea pig Pklr (100716756), naked mole-rat Pklr (101701016), Domestic Rabbit PKLR (100355056)
UniProtKB ID:
Gene ID:
- Human(5313) Summary: The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(18770) pyruvate kinase liver and red blood cell
- Rat(24651) pyruvate kinase, liver and RBC
- Zebrafish(114551) pyruvate kinase, liver and RBC
- domestic cat(100750244) pyruvate kinase deficiency
- domestic cat(101088459) pyruvate kinase, liver and RBC
- dog(490425) pyruvate kinase, liver and RBC
- domestic guinea pig(100716756) pyruvate kinase, liver and RBC
- naked mole-rat(101701016) pyruvate kinase, liver and RBC
- Domestic Rabbit(100355056) pyruvate kinase, liver and RBC
- cow(539579) pyruvate kinase, liver and RBC
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