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MilliporeSigma

PARP1

poly (ADP-ribose) polymerase 1

Synonyms:
ADPRT, ADPRT 1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1
Species:
Human PARP1 (142), Mouse Parp1 (11545), Rat Parp1 (25591), Thale Cress PARP1 (817690), Zebrafish parp1 (560788), chicken PARP1 (396199), dog PARP1 (490385), domestic cat PARP1 (101081434), Horse PARP1 (100058523), cow PARP1 (286764) ...More
UniProtKB ID:
P09874, B1ANJ4, Q8IUZ9
Gene ID:
  • Human(142) Summary: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
  • Mouse(11545) poly (ADP-ribose) polymerase family, member 1
  • Rat(25591) poly (ADP-ribose) polymerase 1
  • Thale Cress(817690) poly [ADP-ribose] polymerase 2
  • Zebrafish(560788) poly (ADP-ribose) polymerase family, member 1
  • chicken(396199) poly (ADP-ribose) polymerase 1
  • dog(490385) poly (ADP-ribose) polymerase 1
  • domestic cat(101081434) poly (ADP-ribose) polymerase 1
  • Horse(100058523) poly (ADP-ribose) polymerase 1
  • cow(286764) poly (ADP-ribose) polymerase 1
  • domestic guinea pig(100733925) poly (ADP-ribose) polymerase 1
  • naked mole-rat(101703207) poly (ADP-ribose) polymerase 1
  • sheep(100135697) poly (ADP-ribose) polymerase 1

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Antibodies

Product Number
Description
Species Reactivity
Application
AB3565
Anti-PARP (214/215) cleavage site Antibody, Chemicon®, from rabbit,
Species Reactivity
bovine, human, mouse, rat
Application
immunocytochemistry
western blot
AB16661
Anti-PARP Poly ADP-ribose Polymerase-1 Antibody, serum, Chemicon®,
Species Reactivity
bovine, human, mouse, rat
Application
ELISA
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
47865-U
Nicotinamide (Niacinamide), analytical standard,
Species
human
N3376
Nicotinamide, ≥98% (HPLC), powder,
Species
human