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Merck

P2RX7

purinergic receptor P2X, ligand-gated ion channel, 7

Synonyms:
P2X7
Species:
Human P2RX7 (5027), Mouse P2rx7 (18439), Rat P2rx7 (29665), Zebrafish p2rx7 (387298), chicken P2RX7 (771952), cow P2RX7 (286814), domestic cat P2RX7 (101097922), Horse P2RX7 (100058464), dog P2RX7 (448778), domestic guinea pig P2rx7 (100379234) ...More
UniProtKB ID:
Q99572, A8K2Z0, O14991, Q96EV7
Gene ID:
  • Human(5027) Summary: The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2010]
  • Mouse(18439) purinergic receptor P2X, ligand-gated ion channel, 7
  • Rat(29665) purinergic receptor P2X, ligand-gated ion channel, 7
  • Zebrafish(387298) purinergic receptor P2X, ligand-gated ion channel, 7
  • chicken(771952) purinergic receptor P2X, ligand-gated ion channel, 7
  • cow(286814) purinergic receptor P2X, ligand-gated ion channel, 7
  • domestic cat(101097922) purinergic receptor P2X, ligand-gated ion channel, 7
  • Horse(100058464) purinergic receptor P2X, ligand-gated ion channel, 7
  • dog(448778) purinergic receptor P2X, ligand-gated ion channel, 7
  • domestic guinea pig(100379234) purinergic receptor P2X, ligand-gated ion channel, 7
  • naked mole-rat(101721795) purinergic receptor P2X, ligand-gated ion channel, 7
  • Domestic Rabbit(100351535) purinergic receptor P2X, ligand-gated ion channel, 7
  • sheep(101103842) purinergic receptor P2X, ligand-gated ion channel, 7

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Antibodies

Product Number
Description
Species Reactivity
Application
AB5246
Anti-P2X7 Receptor Antibody, Chemicon®, from rabbit,
Species Reactivity
rat
Application
immunohistochemistry
western blot
AB5581
Anti-P2X7 Receptor Antibody, extracellular domain, Chemicon®, from rabbit,
Species Reactivity
human, rat
Application
western blot