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Merck

NRAS

neuroblastoma RAS viral (v-ras) oncogene homolog

Synonyms:
ALPS4, N-ras, NRAS1, NS6
Species:
Human NRAS (4893), Mouse Nras (18176), Rat Nras (24605), Zebrafish nras (30380), cow NRAS (506322), dog NRAS (403872), chicken NRAS (419885), sheep NRAS (101102438), domestic guinea pig Nras (100135584), naked mole-rat Nras (101719269)
UniProtKB ID:
P01111, Q14971, Q15104, Q15282
Gene ID:
  • Human(4893) Summary: This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [provided by RefSeq, Jun 2011]
  • Mouse(18176) neuroblastoma ras oncogene
  • Rat(24605) neuroblastoma ras oncogene
  • Zebrafish(30380) neuroblastoma RAS viral (v-ras) oncogene homolog
  • cow(506322) neuroblastoma RAS viral (v-ras) oncogene homolog
  • dog(403872) neuroblastoma RAS viral (v-ras) oncogene homolog
  • chicken(419885) neuroblastoma RAS viral (v-ras) oncogene homolog
  • sheep(101102438) neuroblastoma RAS viral (v-ras) oncogene homolog
  • domestic guinea pig(100135584) neuroblastoma ras oncogene
  • naked mole-rat(101719269) neuroblastoma RAS viral (v-ras) oncogene homolog

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Antibodies

Product Number
Description
Species Reactivity
Application
05-1072
Anti-Ras Antibody, (K-, H-, N-), clone 9A11.2, clone 9A11.2, Upstate®, from mouse,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
05-516
Anti-Ras Antibody, clone RAS10, clone RAS10, Upstate®, from mouse,
Species Reactivity
human, mouse, rat
Application
ELISA
flow cytometry
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot