NKX2-1
NK2 homeobox 1
Synonyms:
BCH, BHC, NK-2, NKX2.1, NKX2A, TEBP, TITF1, TTF-1, TTF1
Species:
Human NKX2-1 (7080), Mouse Nkx2-1 (21869), Rat Nkx2-1 (25628), chicken NKX2-1 (395322), dog NKX2-1 (403940), domestic cat NKX2-1 (101091876), naked mole-rat Nkx2-1 (101703474)
UniProtKB ID:
Gene ID:
- Human(7080) Summary: This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TFF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Apr 2011]
- Mouse(21869) NK2 homeobox 1
- Rat(25628) NK2 homeobox 1
- chicken(395322) NK2 homeobox 1
- dog(403940) NK2 homeobox 1
- domestic cat(101091876) NK2 homeobox 1
- naked mole-rat(101703474) NK2 homeobox 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Nkx2.1 Antibody, clone 8G7-G3-1, ascites fluid, clone 8G7-G3-1, Chemicon®,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot