MSLN
mesothelin
Synonyms:
MPF, SMRP
Species:
Human MSLN (10232), Mouse Msln (56047), Rat Msln (60333), chicken MSLN (416534), dog MSLN (611363), domestic cat MSLN (101091333), cow MSLN (516237), sheep MSLN (101111680), domestic guinea pig Msln (100722390), naked mole-rat Msln (101708230)
UniProtKB ID:
Gene ID:
- Human(10232) Summary: This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010]
- Mouse(56047) mesothelin
- Rat(60333) mesothelin
- chicken(416534) mesothelin
- dog(611363) mesothelin
- domestic cat(101091333) mesothelin
- cow(516237) mesothelin
- sheep(101111680) mesothelin
- domestic guinea pig(100722390) mesothelin
- naked mole-rat(101708230) mesothelin
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