Skip to Content
Merck

MNDA

myeloid cell nuclear differentiation antigen

Synonyms:
PYHIN3
Species:
Human MNDA (4332), Mouse Mnda (381308), Rat Mnda (304988), dog MNDA (488622)
UniProtKB ID:
P41218
Gene ID:
  • Human(4332) Summary: The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons. [provided by RefSeq, Jul 2008]
  • Mouse(381308) myeloid cell nuclear differentiation antigen
  • Rat(304988) myeloid cell nuclear differentiation antigen
  • dog(488622) myeloid cell nuclear differentiation antigen

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.