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Merck

MMP7

matrix metallopeptidase 7 (matrilysin, uterine)

Synonyms:
MMP-7, MPSL1, PUMP-1
Species:
UniProtKB ID:
Gene ID:
  • Human(4316) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
  • Mouse(17393) matrix metallopeptidase 7
  • Rat(25335) matrix metallopeptidase 7
  • chicken(418983) matrix metallopeptidase 7 (matrilysin, uterine)
  • dog(489432) matrix metallopeptidase 7 (matrilysin, uterine)
  • cow(286794) matrix metallopeptidase 7 (matrilysin, uterine)
  • naked mole-rat(101718114) matrix metallopeptidase 7 (matrilysin, uterine)
  • domestic guinea pig(100727130) matrix metallopeptidase 7 (matrilysin, uterine)
  • sheep(100192317) matrix metallopeptidase 7 (matrilysin, uterine)

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ELISA

Product Number
Description
Species
Human MMP-7 ELISA Kit, on for cell culture supernatant,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-MMP-7 Antibody, clone ID-2, clone ID-2, Chemicon®, from mouse,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

Small Molecule - Inhibitor

Product Number
Description
Species
Doxycycline Monohydrate, United States Pharmacopeia (USP) Reference Standard,
Species
human