MICA
MHC class I polypeptide-related sequence A
Synonyms:
MIC-A, PERB11.1
Species:
UniProtKB ID:
Gene ID:
- Human(100507436) Summary: MICA encodes the higly polymorphic MHC (HLA) class I chain-related gene A. The protein product is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]
- chicken(417067) MHC class I polypeptide-related sequence A
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