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Merck

ME1

malic enzyme 1, NADP(+)-dependent, cytosolic

Synonyms:
HUMNDME, MES
Species:
UniProtKB ID:
Gene ID:
  • Human(4199) Summary: This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet. [provided by RefSeq, Jul 2008]
  • Mouse(17436) malic enzyme 1, NADP(+)-dependent, cytosolic
  • Rat(24552) malic enzyme 1, NADP(+)-dependent, cytosolic
  • Zebrafish(768196) malic enzyme 1, NADP(+)-dependent, cytosolic
  • cow(540985) malic enzyme 1, NADP(+)-dependent, cytosolic
  • Horse(100070127) malic enzyme 1, NADP(+)-dependent, cytosolic
  • domestic cat(101082153) malic enzyme 1, NADP(+)-dependent, cytosolic
  • dog(403709) malic enzyme 1, NADP(+)-dependent, cytosolic
  • chicken(374189) malic enzyme 1, NADP(+)-dependent, cytosolic
  • Goat(100860863) malic enzyme 1, NADP(+)-dependent, cytosolic
  • sheep(100189620) malic enzyme 1, NADP(+)-dependent, cytosolic
  • domestic guinea pig(100728635) malic enzyme 1, NADP(+)-dependent, cytosolic
  • naked mole-rat(101717382) malic enzyme 1, NADP(+)-dependent, cytosolic
  • Domestic Rabbit(100355457) malic enzyme 1, NADP(+)-dependent, cytosolic

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