MAPRE1
microtubule-associated protein, RP/EB family, member 1
Synonyms:
EB1
Species:
Human MAPRE1 (22919), Mouse Mapre1 (13589), Rat Mapre1 (114764), chicken MAPRE1 (419288), cow MAPRE1 (507845), domestic cat MAPRE1 (101092509), dog MAPRE1 (100685707), naked mole-rat Mapre1 (101725393), domestic guinea pig Mapre1 (100715917), sheep MAPRE1 (101106097)
UniProtKB ID:
Gene ID:
- Human(22919) Summary: The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family. [provided by RefSeq, Jul 2008]
- Mouse(13589) microtubule-associated protein, RP/EB family, member 1
- Rat(114764) microtubule-associated protein, RP/EB family, member 1
- chicken(419288) microtubule-associated protein, RP/EB family, member 1
- cow(507845) microtubule-associated protein, RP/EB family, member 1
- domestic cat(101092509) microtubule-associated protein, RP/EB family, member 1
- dog(100685707) microtubule-associated protein, RP/EB family, member 1
- naked mole-rat(101725393) microtubule-associated protein, RP/EB family, member 1
- domestic guinea pig(100715917) microtubule-associated protein, RP/EB family, member 1
- sheep(101106097) microtubule-associated protein, RP/EB family, member 1
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