MAPK9
mitogen-activated protein kinase 9
Synonyms:
JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK
Species:
Human MAPK9 (5601), Mouse Mapk9 (26420), Rat Mapk9 (50658), Zebrafish mapk9 (100149273), cow MAPK9 (534125), Horse MAPK9 (100057961), domestic cat MAPK9 (101084765), dog MAPK9 (474652), chicken MAPK9 (395983), naked mole-rat Mapk9 (101698286) ...More
UniProtKB ID:
Gene ID:
- Human(5601) Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Sep 2008]
- Mouse(26420) mitogen-activated protein kinase 9
- Rat(50658) mitogen-activated protein kinase 9
- Zebrafish(100149273) mitogen-activated protein kinase 9
- cow(534125) mitogen-activated protein kinase 9
- Horse(100057961) mitogen-activated protein kinase 9
- domestic cat(101084765) mitogen-activated protein kinase 9
- dog(474652) mitogen-activated protein kinase 9
- chicken(395983) mitogen-activated protein kinase 9
- naked mole-rat(101698286) mitogen-activated protein kinase 9
- Domestic Rabbit(100342664) mitogen-activated protein kinase 9
- domestic guinea pig(100714249) mitogen-activated protein kinase 9
- sheep(101120826) mitogen-activated protein kinase 9
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Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
JNK2α2/SAPK1a Protein, active, 10 µg, Active, N-terminal His-tagged, full length human JNK2α2/SAPK1a, for use in Kinase Assays.,
Species
human