MAPK11
mitogen-activated protein kinase 11
Synonyms:
P38B, P38BETA2, PRKM11, SAPK2, SAPK2B, p38-2, p38Beta
Species:
Human MAPK11 (5600), Mouse Mapk11 (19094), Rat Mapk11 (689314), Zebrafish mapk11 (415185), chicken MAPK11 (417739), dog MAPK11 (607019), domestic cat MAPK11 (101081396), cow MAPK11 (618906), domestic guinea pig Mapk11 (100724974), naked mole-rat Mapk11 (101705370)
UniProtKB ID:
Gene ID:
- Human(5600) Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase. [provided by RefSeq, Jul 2008]
- Mouse(19094) mitogen-activated protein kinase 11
- Rat(689314) mitogen-activated protein kinase 11
- Zebrafish(415185) mitogen-activated protein kinase 11
- chicken(417739) mitogen-activated protein kinase 11
- dog(607019) mitogen-activated protein kinase 11
- domestic cat(101081396) mitogen-activated protein kinase 11
- cow(618906) mitogen-activated protein kinase 11
- domestic guinea pig(100724974) mitogen-activated protein kinase 11
- naked mole-rat(101705370) mitogen-activated protein kinase 11
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