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Merck

LMX1B

LIM homeobox transcription factor 1, beta

Synonyms:
LMX1.2, NPS1
Species:
Human LMX1B (4010), Mouse Lmx1b (16917), Rat Lmx1b (114501), chicken LMX1B (396312), cow LMX1B (100337389), domestic cat LMX1B (101086098), dog LMX1B (403499), domestic guinea pig Lmx1b (100728241), naked mole-rat Lmx1b (101708650), sheep LMX1B (101105482)
UniProtKB ID:
O60663, F8W7W6, O75463, Q5JU95, Q6ISC9
Gene ID:
  • Human(4010) Summary: This gene encodes a member of LIM-homeodomain family of proteins containing two N-terminal zinc-binding LIM domains, 1 homeodomain, and a C-terminal glutamine-rich domain. It functions as a transcription factor, and is essential for the normal development of dorsal limb structures, the glomerular basement membrane, the anterior segment of the eye, and dopaminergic and serotonergic neurons. Mutations in this gene are associated with nail-patella syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
  • Mouse(16917) LIM homeobox transcription factor 1 beta
  • Rat(114501) LIM homeobox transcription factor 1 beta
  • chicken(396312) LIM homeobox transcription factor 1, beta
  • cow(100337389) LIM homeobox transcription factor 1, beta-like
  • domestic cat(101086098) LIM homeobox transcription factor 1, beta
  • dog(403499) LIM homeobox transcription factor 1, beta
  • domestic guinea pig(100728241) LIM homeobox transcription factor 1, beta
  • naked mole-rat(101708650) LIM homeobox transcription factor 1, beta
  • sheep(101105482) LIM homeobox transcription factor 1, beta

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