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Merck

KRAS

Kirsten rat sarcoma viral oncogene homolog

Synonyms:
C-K-RAS, CFC2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS, NS3, RASK2
Species:
Human KRAS (3845), Mouse Kras (16653), Rat Kras (24525), Zebrafish kras (445289), cow KRAS (541140), dog KRAS (403871), chicken KRAS (418207), sheep KRAS (101114005), domestic guinea pig Kras (100716262), naked mole-rat Kras (101718997)
UniProtKB ID:
P01116, A8K8Z5, B0LPF9, P01118, Q96D10
Gene ID:
  • Human(3845) Summary: This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008]
  • Mouse(16653) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • Rat(24525) Kirsten rat sarcoma viral oncogene
  • Zebrafish(445289) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • cow(541140) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • dog(403871) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • chicken(418207) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • sheep(101114005) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • domestic guinea pig(100716262) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • naked mole-rat(101718997) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog

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Antibodies

Product Number
Description
Species Reactivity
Application
MABS194
Anti-c-K-Ras Antibody, clone 234-4.2, clone 234-4.2, from mouse,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
05-1072
Anti-Ras Antibody, (K-, H-, N-), clone 9A11.2, clone 9A11.2, Upstate®, from mouse,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
05-516
Anti-Ras Antibody, clone RAS10, clone RAS10, Upstate®, from mouse,
Species Reactivity
human, mouse, rat
Application
ELISA
flow cytometry
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot