KDR
kinase insert domain receptor (a type III receptor tyrosine kinase)
Synonyms:
CD309, FLK1, VEGFR, VEGFR2
Species:
Human KDR (3791), Mouse Kdr (16542), Rat Kdr (25589), Goat KDR (100860836), sheep KDR (443087), Domestic Rabbit KDR (100008607), domestic guinea pig Kdr (100726761), naked mole-rat Kdr (101726029), Zebrafish kdr (554230), cow KDR (407170) ...More
UniProtKB ID:
Gene ID:
- Human(3791) Summary: Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]
- Mouse(16542) kinase insert domain protein receptor
- Rat(25589) kinase insert domain receptor
- Goat(100860836) kinase insert domain receptor (a type III receptor tyrosine kinase)
- sheep(443087) vascular endothelial growth factor receptor-2
- Domestic Rabbit(100008607) kinase insert domain receptor (a type III receptor tyrosine kinase)
- domestic guinea pig(100726761) kinase insert domain receptor (a type III receptor tyrosine kinase)
- naked mole-rat(101726029) kinase insert domain receptor (a type III receptor tyrosine kinase)
- Zebrafish(554230) kinase insert domain receptor (a type III receptor tyrosine kinase)
- cow(407170) kinase insert domain receptor (a type III receptor tyrosine kinase)
- Horse(100033959) kinase insert domain receptor (a type III receptor tyrosine kinase)
- domestic cat(101090260) kinase insert domain receptor (a type III receptor tyrosine kinase)
- dog(482154) kinase insert domain receptor (a type III receptor tyrosine kinase)
- chicken(395323) kinase insert domain receptor (a type III receptor tyrosine kinase)
- Thale Cress(839585) basic helix-loop-helix protein KIDARI
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ELISA
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-Vascular Endothelial Growth Factor Receptor-2 antibody produced in mouse, clone KDR-1, ascites fluid,
Species Reactivity
human
Application
ELISA
immunohistochemistry
immunohistochemistry
Anti-KDR/Flk-1/VEGFR2 Antibody, clone CH-11, clone CH-11, Upstate®, from mouse,
Species Reactivity
human, mouse
Application
ELISA
immunocytochemistry
western blot
immunocytochemistry
western blot
Anti-phospho-KDR/Flk-1/VEGFR2 (Tyr1054) Antibody, clone D1W, rabbit monoclonal, culture supernatant, clone D1W, Upstate®,
Species Reactivity
human, mouse
Application
western blot
Anti-phospho-VEGFR2/Flk-1/KDR (Tyr1054) Antibody, Upstate®, from rabbit,
Species Reactivity
danio, bovine, chicken, horse, human, mouse, primate, rat, zebrafish
Application
western blot
Proteins
Product Number
Description
Species
KDR Protein, active, 10 µg, Active, N-terminal His6-tagged, recombinant, human KDR amino acids 790-end,
for use in Kinase Assays.,
for use in Kinase Assays.,
Species
human