JARID2
jumonji, AT rich interactive domain 2
Synonyms:
JMJ
Species:
Human JARID2 (3720), Mouse Jarid2 (16468), Rat Jarid2 (681740), fruit fly Jarid2 (39103), chicken JARID2 (420839), domestic cat JARID2 (101093520), cow JARID2 (528253), Horse JARID2 (100051819), dog JARID2 (478729), sheep JARID2 (101113542) ...More
UniProtKB ID:
Gene ID:
- Human(3720) Summary: This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies. [provided by RefSeq, May 2012]
- Mouse(16468) jumonji, AT rich interactive domain 2
- Rat(681740) jumonji, AT rich interactive domain 2
- fruit fly(39103) Jumonji, AT rich interactive domain 2
- chicken(420839) jumonji, AT rich interactive domain 2
- domestic cat(101093520) jumonji, AT rich interactive domain 2
- cow(528253) jumonji, AT rich interactive domain 2
- Horse(100051819) jumonji, AT rich interactive domain 2
- dog(478729) jumonji, AT rich interactive domain 2
- sheep(101113542) jumonji, AT rich interactive domain 2
- domestic guinea pig(100728421) jumonji, AT rich interactive domain 2
- naked mole-rat(101714621) jumonji, AT rich interactive domain 2
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