ITGAV
integrin, alpha V
Synonyms:
CD51, MSK8, VNRA, VTNR
Species:
Human ITGAV (3685), Mouse Itgav (16410), Rat Itgav (296456), sheep ITGAV (443143), Domestic Rabbit ITGAV (100008956), domestic guinea pig Itgav (100728575), naked mole-rat Itgav (101717672), Zebrafish itgav (100151255), cow ITGAV (281875), Horse ITGAV (100068706) ...More
UniProtKB ID:
Gene ID:
- Human(3685) Summary: This gene encodes a protein that is a member of the integrin superfamily. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein undergoes post-translational cleavage to yield disulfide-linked heavy and light chains that combine with multiple integrin beta chains to form different integrins. This protein has been shown to heterodimerize with beta 1, beta 3, beta 5, beta 6, and beta 8; the heterodimer of alpha v and beta 3 is the Vitronectin receptor. This protein interacts with several extracellular matrix proteins to mediate cell adhesion and may play a role in cell migration. It is proposed that this protein may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, May 2013]
- Mouse(16410) integrin alpha V
- Rat(296456) integrin, alpha V
- sheep(443143) integrin, alpha V
- Domestic Rabbit(100008956) integrin, alpha V
- domestic guinea pig(100728575) integrin, alpha V
- naked mole-rat(101717672) integrin, alpha V
- Zebrafish(100151255) integrin, alpha V
- cow(281875) integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
- Horse(100068706) integrin, alpha V
- domestic cat(101085820) integrin, alpha V
- dog(488437) integrin, alpha V
- chicken(396420) integrin, alpha V
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Integrin αV Antibody, extracellular, clone AV1, azide free, culture supernatant, clone AV1, Chemicon®,
Species Reactivity
human
Application
flow cytometry
western blot
western blot
Anti-Integrin αVβ3 Antibody, clone LM609, Alexa Fluor™488 conjugated, clone LM609, Chemicon®, from mouse,
Species Reactivity
avian, bovine, canine, chicken, human, monkey, pig, rabbit
Application
flow cytometry
immunofluorescence
immunofluorescence
Anti-Integrin αV Antibody, clone P3G8, azide free, clone P3G8, Chemicon®, from mouse,
Species Reactivity
human
Application
ELISA
flow cytometry
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
flow cytometry
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
Anti-Integrin αVβ3 Antibody, clone LM609, biotin conjugated, clone LM609, Chemicon®, from mouse,
Species Reactivity
avian, bovine, canine, chicken, human, monkey, pig, rabbit
Application
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
immunohistochemistry
immunoprecipitation (IP)
Anti-Integrin αV Antibody, clone P3G8, clone P3G8, Chemicon®, from mouse,
Species Reactivity
human
Application
ELISA
flow cytometry
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
flow cytometry
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)