IRF6
interferon regulatory factor 6
Synonyms:
LPS, OFC6, PIT, PPS, PPS1, VWS, VWS1
Species:
Human IRF6 (3664), Mouse Irf6 (54139), Rat Irf6 (364081), Zebrafish irf6 (393570), dog IRF6 (480015), cow IRF6 (614253), Horse IRF6 (100051502), domestic cat IRF6 (101087375), chicken IRF6 (419863), domestic guinea pig Irf6 (100729739) ...More
UniProtKB ID:
Gene ID:
- Human(3664) Summary: This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2011]
- Mouse(54139) interferon regulatory factor 6
- Rat(364081) interferon regulatory factor 6
- Zebrafish(393570) interferon regulatory factor 6
- dog(480015) interferon regulatory factor 6
- cow(614253) interferon regulatory factor 6
- Horse(100051502) interferon regulatory factor 6
- domestic cat(101087375) interferon regulatory factor 6
- chicken(419863) interferon regulatory factor 6
- domestic guinea pig(100729739) interferon regulatory factor 6
- naked mole-rat(101711748) interferon regulatory factor 6
- sheep(443083) interferon regulatory factor 6
- Domestic Rabbit(100349520) interferon regulatory factor 6
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