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ILF2

interleukin enhancer binding factor 2

Synonyms:
NF45, PRO3063
Species:
UniProtKB ID:
Gene ID:
  • Human(3608) Summary: The protein encoded by this gene is the 45 kDa component of nuclear factor of activated T-cells (NFAT), a heterodimer of 45 kDa and 90 kDa proteins. NFAT is a transcription factor required for T-cell expression of the interleukin 2 gene. It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. The complex has been shown to repair DNA breaks by nonhomologous end joining and can also negatively regulate the microRNA processing pathway. Alternative splicing results in multiple transcript variants. Related pseudogenes have been found on chromosomes 3 and 14. [provided by RefSeq, Jun 2012]
  • Mouse(67781) interleukin enhancer binding factor 2
  • Rat(310612) interleukin enhancer binding factor 2
  • Zebrafish(406517) interleukin enhancer binding factor 2
  • chicken(425709) interleukin enhancer binding factor 2, 45kDa
  • domestic cat(101080940) interleukin enhancer binding factor 2, 45kDa
  • Horse(100056483) interleukin enhancer binding factor 2, 45kDa
  • cow(539760) interleukin enhancer binding factor 2, 45kDa
  • dog(480139) interleukin enhancer binding factor 2, 45kDa
  • sheep(101106476) interleukin enhancer binding factor 2, 45kDa
  • domestic guinea pig(100728552) interleukin enhancer binding factor 2
  • naked mole-rat(101714995) interleukin enhancer binding factor 2

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