IL2
interleukin 2
Synonyms:
IL-2, TCGF, lymphokine
Species:
Human IL2 (3558), Mouse Il2 (16183), Rat Il2 (116562), chicken IL2 (373958), cow IL2 (280822), Horse IL2 (100034204), domestic cat IL2 (751114), dog IL2 (403989), sheep IL2 (443401), Domestic Rabbit IL2 (100302458) ...More
UniProtKB ID:
Gene ID:
- Human(3558) Summary: The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008]
- Mouse(16183) interleukin 2
- Rat(116562) interleukin 2
- chicken(373958) interleukin 2
- cow(280822) interleukin 2
- Horse(100034204) interleukin 2
- domestic cat(751114) interleukin 2
- dog(403989) interleukin 2
- sheep(443401) interleukin 2
- Domestic Rabbit(100302458) interleukin 2
- domestic guinea pig(100379540) interleukin 2
- naked mole-rat(101720581) interleukin 2
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