Skip to Content
Merck

HNF1B

HNF1 homeobox B

Synonyms:
FJHN, HNF-1B, HNF1beta, HNF2, HPC11, LF-B3, LFB3, MODY5, TCF-2, TCF2, VHNF1
Species:
UniProtKB ID:
Gene ID:
  • Human(6928) Summary: This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
  • Mouse(21410) HNF1 homeobox B
  • Rat(25640) HNF1 homeobox B
  • chicken(427838) HNF1 homeobox B
  • cow(503581) HNF1 homeobox B
  • Horse(100057769) HNF1 homeobox B
  • domestic cat(101081843) HNF1 homeobox B
  • dog(610402) HNF1 homeobox B
  • domestic guinea pig(100734532) HNF1 homeobox B
  • naked mole-rat(101711309) HNF1 homeobox B

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.