HK1
hexokinase 1
Synonyms:
HK1-ta, HK1-tb, HK1-tc, HKD, HKI, HMSNR, HXK1
Species:
Human HK1 (3098), Mouse Hk1 (15275), Rat Hk1 (25058), Zebrafish hk1 (406791), cow HK1 (280817), Horse HK1 (100072687), domestic cat HK1 (101098403), dog HK1 (479234), chicken HK1 (373889), Thale Cress HK1 (816291) ...More
UniProtKB ID:
Gene ID:
- Human(3098) Summary: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus; the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein. [provided by RefSeq, Apr 2009]
- Mouse(15275) hexokinase 1
- Rat(25058) hexokinase 1
- Zebrafish(406791) hexokinase 1
- cow(280817) hexokinase 1
- Horse(100072687) hexokinase 1
- domestic cat(101098403) hexokinase 1
- dog(479234) hexokinase 1
- chicken(373889) hexokinase 1
- Thale Cress(816291) histidine kinase 1
- sheep(100036759) hexokinase 1
- Domestic Rabbit(100340945) hexokinase 1
- domestic guinea pig(100730936) hexokinase 1
- naked mole-rat(101709130) hexokinase 1
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