HAND1
heart and neural crest derivatives expressed 1
Synonyms:
Hxt, Thing1, bHLHa27, eHand
Species:
Human HAND1 (9421), Mouse Hand1 (15110), Rat Hand1 (59112), chicken HAND1 (395812), dog HAND1 (489164), cow HAND1 (517952), domestic cat HAND1 (101096445), sheep HAND1 (443353), domestic guinea pig Hand1 (100722914), naked mole-rat Hand1 (101721169)
UniProtKB ID:
Gene ID:
- Human(9421) Summary: The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation. [provided by RefSeq, Jul 2008]
- Mouse(15110) heart and neural crest derivatives expressed transcript 1
- Rat(59112) heart and neural crest derivatives expressed 1
- chicken(395812) heart and neural crest derivatives expressed 1
- dog(489164) heart and neural crest derivatives expressed 1
- cow(517952) heart and neural crest derivatives expressed 1
- domestic cat(101096445) heart and neural crest derivatives expressed 1
- sheep(443353) heart and neural crest derivatives expressed 1
- domestic guinea pig(100722914) heart and neural crest derivatives expressed 1
- naked mole-rat(101721169) heart and neural crest derivatives expressed 1
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