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Merck

GRIN2B

glutamate receptor, ionotropic, N-methyl D-aspartate 2B

Synonyms:
GluN2B, MRD6, NMDAR2B, NR2B, hNR3
Species:
UniProtKB ID:
Gene ID:
  • Human(2904) Summary: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain. [provided by RefSeq, Jul 2008]
  • Mouse(14812) glutamate receptor, ionotropic, NMDA2B (epsilon 2)
  • Rat(24410) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • chicken(417965) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • dog(494009) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • domestic cat(101094356) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • Horse(100063746) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • cow(537804) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • domestic guinea pig(100731840) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • naked mole-rat(101723091) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • sheep(101118179) glutamate receptor, ionotropic, N-methyl D-aspartate 2B

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Small Molecule - Agonist

Product Number
Description
Species
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Species
rat, human
L-Glutamic acid, FCC,
Species
rat, human
L-Glutamic acid, BioUltra, ≥99.5% (NT),
Species
rat, human

Small Molecule - Antagonist

Product Number
Description
Species
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Species
rat, human
L-Glutamic acid, FCC,
Species
rat, human
L-Glutamic acid, BioUltra, ≥99.5% (NT),
Species
rat, human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-NMDAR2B phospho Tyr1252 Antibody, Chemicon®, from rabbit,
Species Reactivity
rat
Application
western blot
Anti-NMDAR2B Antibody, pain, serum, Chemicon®,
Species Reactivity
human, mouse, rat
Application
immunoprecipitation (IP)
western blot
Anti-NMDAR2B Antibody, phosphoTyr 1472, Chemicon®, from rabbit,
Species Reactivity
rat
Application
western blot
Anti-NR2B Antibody, clone BWJHL, clone BWJHL, Upstate®, from mouse,
Species Reactivity
human, rat
Application
western blot
Anti-phospho-NR2B (Ser1303) Antibody, Upstate®, from rabbit,
Species Reactivity
human, mouse, rat
Application
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Species
rat, human
L-Glutamic acid, FCC,
Species
rat, human
L-Glutamic acid, BioUltra, ≥99.5% (NT),
Species
rat, human