GDNF
glial cell derived neurotrophic factor
Synonyms:
ATF1, ATF2, HFB1-GDNF, HSCR3
Species:
Human GDNF (2668), Mouse Gdnf (14573), Rat Gdnf (25453), sheep GDNF (101117619), domestic guinea pig Gdnf (100717276), naked mole-rat Gdnf (101700544), chicken GDNF (395569), cow GDNF (386587), Horse GDNF (100067053), domestic cat GDNF (101097871)
UniProtKB ID:
Gene ID:
- Human(2668) Summary: This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene may be associated with Hirschsprung disease. [provided by RefSeq, Jun 2010]
- Mouse(14573) glial cell line derived neurotrophic factor
- Rat(25453) glial cell derived neurotrophic factor
- sheep(101117619) glial cell derived neurotrophic factor
- domestic guinea pig(100717276) glial cell derived neurotrophic factor
- naked mole-rat(101700544) glial cell derived neurotrophic factor
- chicken(395569) glial cell derived neurotrophic factor
- cow(386587) glial cell derived neurotrophic factor
- Horse(100067053) glial cell derived neurotrophic factor
- domestic cat(101097871) glial cell derived neurotrophic factor
- dog(489224) glial cell derived neurotrophic factor
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ELISA
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Glial Derived Neurotrophic Factor Antibody, Chemicon®, from chicken,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Anti-Glial Derived Neurotrophic Factor Antibody, Chemicon®, from sheep,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
Anti-Glial Derived Neurotrophic Factor Antibody, serum, Chemicon®,
Species Reactivity
human, mouse, rat
Application
western blot