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Merck

FZD4

frizzled family receptor 4

Synonyms:
CD344, EVR1, FEVR, FZD4S, Fz-4, Fz4, FzE4, GPCR, hFz4
Species:
UniProtKB ID:
Gene ID:
  • Human(8322) Summary: This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq, Jul 2008]
  • Mouse(14366) frizzled homolog 4 (Drosophila)
  • Rat(64558) frizzled family receptor 4
  • Zebrafish(30363) frizzled homolog 4
  • cow(445416) frizzled family receptor 4
  • Horse(100050465) frizzled family receptor 4
  • domestic cat(101093710) frizzled family receptor 4
  • dog(485149) frizzled family receptor 4
  • chicken(373887) frizzled family receptor 4
  • naked mole-rat(101700404) frizzled family receptor 4
  • domestic guinea pig(100714941) frizzled family receptor 4
  • sheep(101101932) frizzled family receptor 4

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