FGF18
fibroblast growth factor 18
Synonyms:
FGF-18, ZFGF5
Species:
Human FGF18 (8817), Mouse Fgf18 (14172), Rat Fgf18 (29369), sheep FGF18 (780460), naked mole-rat Fgf18 (101718946), domestic guinea pig Fgf18 (100715152), chicken FGF18 (395453), domestic cat FGF18 (101098518), cow FGF18 (533929), dog FGF18 (611641)
UniProtKB ID:
Gene ID:
- Human(8817) Summary: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures. [provided by RefSeq, Jul 2008]
- Mouse(14172) fibroblast growth factor 18
- Rat(29369) fibroblast growth factor 18
- sheep(780460) fibroblast growth factor 18
- naked mole-rat(101718946) fibroblast growth factor 18
- domestic guinea pig(100715152) fibroblast growth factor 18
- chicken(395453) fibroblast growth factor 18
- domestic cat(101098518) fibroblast growth factor 18
- cow(533929) fibroblast growth factor 18
- dog(611641) fibroblast growth factor 18
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