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Merck

FGA

fibrinogen alpha chain

Synonyms:
Fib2
Species:
UniProtKB ID:
Gene ID:
  • Human(2243) Summary: The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus. [provided by RefSeq, Jul 2008]
  • Mouse(14161) fibrinogen alpha chain
  • Rat(361969) fibrinogen alpha chain
  • sheep(101102090) fibrinogen alpha chain
  • Domestic Rabbit(100353616) fibrinogen alpha chain
  • domestic guinea pig(100720646) fibrinogen alpha chain
  • naked mole-rat(101697611) fibrinogen alpha chain
  • Zebrafish(378986) fibrinogen alpha chain
  • chicken(396307) fibrinogen alpha chain
  • dog(475473) fibrinogen alpha chain
  • domestic cat(101092934) fibrinogen alpha chain
  • Horse(100069763) fibrinogen alpha chain
  • cow(522039) fibrinogen alpha chain

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ELISA

Product Number
Description
Species
Human D-Dimer ELISA Kit, for serum, plasma, cell culture supernatants and urine,
Species
human

Proteins

Product Number
Description
Species
Fibrinogen from human plasma, 50-70% protein (≥80% of protein is clottable),
Species
human