Skip to Content
Merck

EGFR

epidermal growth factor receptor

Synonyms:
ERBB, ERBB1, HER1, PIG61, mENA
Species:
UniProtKB ID:
Gene ID:
  • Human(1956) Summary: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
  • Mouse(13649) epidermal growth factor receptor
  • Rat(24329) epidermal growth factor receptor
  • fruit fly(37455) Epidermal growth factor receptor
  • cow(407217) epidermal growth factor receptor
  • Horse(100067755) epidermal growth factor receptor
  • domestic cat(100510799) epidermal growth factor receptor
  • dog(404306) epidermal growth factor receptor
  • chicken(396494) epidermal growth factor receptor
  • domestic guinea pig(100725363) epidermal growth factor receptor
  • naked mole-rat(101723771) epidermal growth factor receptor
  • sheep(780479) epidermal growth factor receptor

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Product Number
Description
Species
Phospho-EGFR (pTyr1045) and pan-EGFR ELISA Kit, for detection of human phospho-egfr (pTyr1045) and pan-egfr in cell and tissue lysates,
Species
human
Cell-Based ELISA for detecting phospho-EGFR (pTyr845) in cultured cell lines, 96 assays,
Species
human
Phospho-EGFR (pSer1070) ELISA Kit, for detection of human, mouse or rat phospho-egfr (pSer1070) in cell and tissue lysates,
Species
human
Phospho-EGFR (pTyr1086) ELISA Kit, for detection of human phospho-egfr (pTyr1086) in cell and tissue lysates,
Species
human
Phospho-EGFR (pTyr1086) and pan-EGFR ELISA Kit, for detection of human phospho-egfr (pTyr1086) and pan-egfr in cell and tissue lysates,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-EGFR Antibody, clone LA22, clone LA22, Upstate®, from mouse,
Species Reactivity
human
Application
immunocytochemistry
immunoprecipitation (IP)

western blot
Milli-Mark® Anti-EGFR-FITC Antibody, Milli-Mark®, from rabbit,
Species Reactivity
human
Application
flow cytometry
Anti-EGFR Antibody, neutralizing, clone LA1, clone LA1, Upstate®, from mouse,
Species Reactivity
human
Application
immunocytochemistry
immunohistochemistry

immunoprecipitation (IP)

neutralization

western blot
Anti-phospho-EGFR (Tyr1086) Antibody, Upstate®, from rabbit,
Species Reactivity
human
Application
western blot
Anti-phospho-EGFR (Tyr1148) Antibody, Upstate®, from rabbit,
Species Reactivity
human
Application
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Gefitinib, European Pharmacopoeia (EP) Reference Standard,
Species
human
Gefitinib for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human