EGFR
epidermal growth factor receptor
Synonyms:
ERBB, ERBB1, HER1, PIG61, mENA
Species:
Human EGFR (1956), Mouse Egfr (13649), Rat Egfr (24329), fruit fly Egfr (37455), cow EGFR (407217), Horse EGFR (100067755), domestic cat EGFR (100510799), dog EGFR (404306), chicken EGFR (396494), domestic guinea pig Egfr (100725363) ...More
UniProtKB ID:
Gene ID:
- Human(1956) Summary: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
- Mouse(13649) epidermal growth factor receptor
- Rat(24329) epidermal growth factor receptor
- fruit fly(37455) Epidermal growth factor receptor
- cow(407217) epidermal growth factor receptor
- Horse(100067755) epidermal growth factor receptor
- domestic cat(100510799) epidermal growth factor receptor
- dog(404306) epidermal growth factor receptor
- chicken(396494) epidermal growth factor receptor
- domestic guinea pig(100725363) epidermal growth factor receptor
- naked mole-rat(101723771) epidermal growth factor receptor
- sheep(780479) epidermal growth factor receptor
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Product Number
Description
Species
Human EGFR / ErbB1 ELISA Kit, for serum, plasma, cell culture supernatants and urine,
Species
human
Phospho-EGFR (pTyr992) and pan-EGFR ELISA Kit, for detection of human phospho-egfr (pTyr992) and pan-egfr in cell and tissue lysates,
Species
human
Cell-Based ELISA for detecting phospho-EGFR (pTyr992) in cultured cell lines, 96 assays,
Species
human
Cell-Based phospho-EGFR ELISA Sampler Kit, for detecting phospho-egfr(pTyr845), phospho-egfr(pTyr992), phospho-egfr(pTyr1068) and phospho-egfr in cultured cell lines,
Species
human
Phospho-EGFR (pTyr1045) ELISA Kit, for detection of human phospho-egfr (pTyr1045) in cell and tissue lysates,
Species
human
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-Epidermal Growth Factor Receptor antibody produced in mouse, clone F4, ascites fluid,
Species Reactivity
human
Application
ELISA
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot
Anti-phospho-EGFR (Tyr1148) Antibody, Upstate®, from rabbit,
Species Reactivity
human
Application
western blot
Anti-phospho-EGFR (Tyr845) Antibody, Upstate®, from rabbit,
Species Reactivity
human
Application
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Milli-Mark® Anti-EGFR-FITC Antibody, Milli-Mark®, from rabbit,
Species Reactivity
human
Application
flow cytometry
Anti-phospho-EGFR (Tyr1086) Antibody, Upstate®, from rabbit,
Species Reactivity
human
Application
western blot