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Merck

DDX39B

DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B

Synonyms:
BAT1, D6S81E, UAP56
Species:
Human DDX39B (7919), Mouse Ddx39b (53817), Rat Ddx39b (114612), Zebrafish ddx39b (406249), cow DDX39B (540191), Horse DDX39B (100146384), domestic cat DDX39B (101083847), dog DDX39B (474839), domestic guinea pig Ddx39b (100723839), naked mole-rat Ddx39b (101719937)
UniProtKB ID:
Q13838, B0S8C0, O43496, Q0EFA1, Q2L6F9, Q53GL9, Q5RJ64, Q5RJ66
Gene ID:
  • Human(7919) Summary: This gene encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing. The encoded protein is an essential splicing factor required for association of U2 small nuclear ribonucleoprotein with pre-mRNA, and it also plays an important role in mRNA export from the nucleus to the cytoplasm. This gene belongs to a cluster of genes localized in the vicinity of the genes encoding tumor necrosis factor alpha and tumor necrosis factor beta. These genes are all within the human major histocompatibility complex class III region. Mutations in this gene may be associated with rheumatoid arthritis. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on both chromosomes 6 and 11. Read-through transcription also occurs between this gene and the upstream ATP6V1G2 (ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2) gene. [provided by RefSeq, Feb 2011]
  • Mouse(53817) DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
  • Rat(114612) DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
  • Zebrafish(406249) DEAD (Asp-Glu-Ala-Asp) box polypeptide 39b
  • cow(540191) DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
  • Horse(100146384) DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
  • domestic cat(101083847) DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
  • dog(474839) DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
  • domestic guinea pig(100723839) DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
  • naked mole-rat(101719937) DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
  • sheep(101101929) DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B

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