Skip to Content
Merck

CYP2C18

cytochrome P450, family 2, subfamily C, polypeptide 18

Synonyms:
CPCI, CYP2C, CYP2C17, P450-6B/29C, P450IIC17
Species:
Human CYP2C18 (1562), sheep CYP2C18 (100568290), chicken CYP2C18 (414841), cow CYP2C18 (535243), dog CYP2C18 (415122)
UniProtKB ID:
P33260, B2R8K2, Q16703, Q16751, Q4VAT5, Q6GRG1
Gene ID:
  • Human(1562) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum but its specific substrate has not yet been determined. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. An additional gene, CYP2C17, was once thought to exist; however, CYP2C17 is now considered an artefact based on a chimera of CYP2C18 and CYP2C19. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • sheep(100568290) cytochrome P450 2C18
  • chicken(414841) cytochrome P450, family 2, subfamily C, polypeptide 18
  • cow(535243) cytochrome P450, family 2, subfamily C, polypeptide 18
  • dog(415122) cytochrome P450 2C21

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.