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Merck

COL18A1

collagen, type XVIII, alpha 1

Synonyms:
KNO, KNO1, KS
Species:
Human COL18A1 (80781), Mouse Col18a1 (12822), Rat Col18a1 (85251), Zebrafish col18a1 (564123), cow COL18A1 (508076), domestic cat COL18A1 (101086496), dog COL18A1 (100687767), dog COL18A1 (100126771), chicken COL18A1 (373978), sheep COL18A1 (101106232) ...More
UniProtKB ID:
P39060, A8MVI4, Q58EX6, Q6RZ39, Q6RZ40, Q6RZ41, Q8N4S4, Q8WXI5
Gene ID:
  • Human(80781) Summary: This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin, a potent antiangiogenic protein. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
  • Mouse(12822) collagen, type XVIII, alpha 1
  • Rat(85251) collagen, type XVIII, alpha 1
  • Zebrafish(564123) collagen type XVIII, alpha 1
  • cow(508076) collagen, type XVIII, alpha 1
  • domestic cat(101086496) collagen, type XVIII, alpha 1
  • dog(100687767) collagen, type XVIII, alpha 1
  • dog(100126771) collagen, type XVIII, alpha 1
  • chicken(373978) collagen, type XVIII, alpha 1
  • sheep(101106232) collagen, type XVIII, alpha 1
  • naked mole-rat(101705854) collagen, type XVIII, alpha 1
  • domestic guinea pig(100733184) collagen, type XVIII, alpha 1

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ELISA

Product Number
Description
Species
RAB0095
Human Endostatin ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
05-579
Anti-Endostatin Antibody, clone 1837.46, clone 1837.46, Upstate®, from mouse,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot