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Merck

CHRNB3

cholinergic receptor, nicotinic, beta 3 (neuronal)

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(1142) Summary: The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are (hetero)pentamers composed of homologous subunits. The subunits that make up the muscle and neuronal forms of nAChRs are encoded by separate genes and have different primary structure. There are several subtypes of neuronal nAChRs that vary based on which homologous subunits are arranged around the central channel. They are classified as alpha-subunits if, like muscle alpha-1 (MIM 100690), they have a pair of adjacent cysteines as part of the presumed acetylcholine binding site. Subunits lacking these cysteine residues are classified as beta-subunits (Groot Kormelink and Luyten, 1997 [PubMed 9009220]
  • Mouse(108043) cholinergic receptor, nicotinic, beta polypeptide 3
  • Rat(171131) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • chicken(395604) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • cow(521702) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • Horse(100054095) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • dog(482837) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • domestic cat(101098624) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • sheep(101122833) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • Domestic Rabbit(100355898) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • naked mole-rat(101706291) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • domestic guinea pig(100723424) cholinergic receptor, nicotinic, beta 3 (neuronal)

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Small Molecule - Blocker

Product Number
Description
Species
Tetraethylammonium chloride, ≥98% (titration),
Species
human