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Merck

CHRNB1

cholinergic receptor, nicotinic, beta 1 (muscle)

Synonyms:
ACHRB, CHRNB, CMS1D, CMS2A, SCCMS
Species:
UniProtKB ID:
Gene ID:
  • Human(1140) Summary: The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome. [provided by RefSeq, Jul 2008]
  • Mouse(11443) cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)
  • Rat(24261) cholinergic receptor, nicotinic, beta 1 (muscle)
  • Zebrafish(100006941) cholinergic receptor, nicotinic, beta 1 (muscle)
  • cow(282179) cholinergic receptor, nicotinic, beta 1 (muscle)
  • Horse(100072990) cholinergic receptor, nicotinic, beta 1 (muscle)
  • domestic cat(101097433) cholinergic receptor, nicotinic, beta 1 (muscle)
  • dog(489473) cholinergic receptor, nicotinic, beta 1 (muscle)
  • sheep(101121614) cholinergic receptor, nicotinic, beta 1 (muscle)
  • Domestic Rabbit(100357163) cholinergic receptor, nicotinic, beta 1 (muscle)
  • naked mole-rat(101723288) cholinergic receptor, nicotinic, beta 1 (muscle)
  • domestic guinea pig(100714100) cholinergic receptor, nicotinic, beta 1 (muscle)

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Small Molecule - Agonist

Product Number
Description
Species
(−)-Nicotine, ≥99% (GC), liquid,
Species
human, mouse, rat

Small Molecule - Antagonist

Product Number
Description
Species
(−)-Nicotine, ≥99% (GC), liquid,
Species
human, mouse, rat

Small Molecule - Blocker

Product Number
Description
Species
Tetraethylammonium chloride, ≥98% (titration),
Species
human