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Merck

CHRNA3

cholinergic receptor, nicotinic, alpha 3 (neuronal)

Synonyms:
LNCR2, NACHRA3, PAOD2
Species:
UniProtKB ID:
Gene ID:
  • Human(1136) Summary: This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009]
  • Mouse(110834) cholinergic receptor, nicotinic, alpha polypeptide 3
  • Rat(25101) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • Zebrafish(568467) cholinergic receptor, nicotinic, alpha 3
  • dog(482111) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • domestic cat(100037403) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • cow(282702) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • chicken(386578) cholinergic receptor, nicotinic, alpha 3
  • naked mole-rat(101701279) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • domestic guinea pig(100730977) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • sheep(101123239) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • Domestic Rabbit(100342666) cholinergic receptor, nicotinic, alpha 3 (neuronal)

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Small Molecule - Agonist

Product Number
Description
Species
(±)-Nicotine, ≥99% (TLC), liquid,
Species
human, rat
(−)-Nicotine, ≥99% (GC), liquid,
Species
human, mouse, rat

Small Molecule - Antagonist

Product Number
Description
Species
(±)-Nicotine, ≥99% (TLC), liquid,
Species
human, rat
(−)-Nicotine, ≥99% (GC), liquid,
Species
human, mouse, rat

Small Molecule - Blocker

Product Number
Description
Species
Tetraethylammonium chloride, ≥98% (titration),
Species
human