CHIT1
chitinase 1 (chitotriosidase)
CHI3, CHIT, CHITD
Human CHIT1 (1118), Mouse Chit1 (71884), Rat Chit1 (289032), domestic cat CHIT1 (101081696), cow CHIT1 (789394), Horse CHIT1 (100065255), naked mole-rat Chit1 (101702614), domestic guinea pig Chit1 (100721444), Domestic Rabbit CHIT1 (100338170)
- Human(1118) Summary: Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jan 2012]
- Mouse(71884) chitinase 1 (chitotriosidase)
- Rat(289032) chitinase 1 (chitotriosidase)
- domestic cat(101081696) chitinase 1 (chitotriosidase)
- cow(789394) chitinase 1 (chitotriosidase)
- Horse(100065255) chitinase 1 (chitotriosidase)
- naked mole-rat(101702614) chitinase 1 (chitotriosidase)
- domestic guinea pig(100721444) chitinase 1 (chitotriosidase)
- Domestic Rabbit(100338170) chitinase 1 (chitotriosidase)
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