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Merck

CDKN1B

cyclin-dependent kinase inhibitor 1B (p27, Kip1)

Synonyms:
CDKN4, KIP1, MEN1B, MEN4, P27KIP1
Species:
Human CDKN1B (1027), Mouse Cdkn1b (12576), Rat Cdkn1b (83571), chicken CDKN1B (374106), dog CDKN1B (403429), cow CDKN1B (512613), domestic cat CDKN1B (493958), chicken CDKN1B (769872), naked mole-rat Cdkn1b (101698721), domestic guinea pig Cdkn1b (100729359) ...More
UniProtKB ID:
P46527, Q16307, Q5U0H2, Q9BUS6
Gene ID:
  • Human(1027) Summary: This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. [provided by RefSeq, Jul 2008]
  • Mouse(12576) cyclin-dependent kinase inhibitor 1B
  • Rat(83571) cyclin-dependent kinase inhibitor 1B
  • chicken(374106) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • dog(403429) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • cow(512613) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • domestic cat(493958) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • chicken(769872) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • naked mole-rat(101698721) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • domestic guinea pig(100729359) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • sheep(100127219) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • Domestic Rabbit(100009037) cyclin-dependent kinase inhibitor 1B (p27, Kip1)

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Antibodies

Product Number
Description
Species Reactivity
Application
06-445
Anti-Kip1 (p27) Antibody, Upstate®, from rabbit,
Species Reactivity
human, rabbit, rat
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
07-500
Anti-p47-phox (mouse) Antibody, Upstate®, from rabbit,
Species Reactivity
mouse
Application
western blot
06-996
Anti-phospho-Kip1 (Thr187) Antibody, Upstate®, from rabbit,
Species Reactivity
human, mouse, rat
Application
western blot