CD86
CD86 molecule
Synonyms:
B7-2, B7.2, B70, CD28LG2, LAB72
Species:
Human CD86 (942), Mouse Cd86 (12524), Rat Cd86 (56822), Domestic Rabbit CD86 (100008999), domestic guinea pig Cd86 (101787434), naked mole-rat Cd86 (101724342), chicken CD86 (427944), cow CD86 (414345), domestic cat CD86 (493704), dog CD86 (403764)
UniProtKB ID:
Gene ID:
- Human(942) Summary: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]
- Mouse(12524) CD86 antigen
- Rat(56822) CD86 molecule
- Domestic Rabbit(100008999) CD86 molecule
- domestic guinea pig(101787434) CD86 molecule
- naked mole-rat(101724342) CD86 molecule
- chicken(427944) CD86 molecule
- cow(414345) CD86 molecule
- domestic cat(493704) CD86 molecule
- dog(403764) CD86 molecule
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