CD68
CD68 molecule
Synonyms:
GP110, LAMP4, SCARD1
Species:
Human CD68 (968), Mouse Cd68 (12514), Rat Cd68 (287435), naked mole-rat Cd68 (101698291), domestic guinea pig Cd68 (100712726), sheep CD68 (101102500), cow CD68 (504960), Horse CD68 (100034045), domestic cat CD68 (101099002), dog CD68 (489476)
UniProtKB ID:
Gene ID:
- Human(968) Summary: This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]
- Mouse(12514) CD68 antigen
- Rat(287435) Cd68 molecule
- naked mole-rat(101698291) CD68 molecule
- domestic guinea pig(100712726) CD68 molecule
- sheep(101102500) CD68 molecule
- cow(504960) CD68 molecule
- Horse(100034045) CD68 molecule
- domestic cat(101099002) CD68 molecule
- dog(489476) CD68 molecule
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