CD2AP
CD2-associated protein
Synonyms:
CMS
Species:
Human CD2AP (23607), Mouse Cd2ap (12488), Rat Cd2ap (316258), naked mole-rat Cd2ap (101713086), domestic guinea pig Cd2ap (100731393), sheep CD2AP (101117542), Domestic Rabbit CD2AP (100341696), Zebrafish cd2ap (494040), domestic cat CD2AP (101091623), dog CD2AP (474928) ...More
UniProtKB ID:
Gene ID:
- Human(23607) Summary: This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease. [provided by RefSeq, Jul 2008]
- Mouse(12488) CD2-associated protein
- Rat(316258) CD2-associated protein
- naked mole-rat(101713086) CD2-associated protein
- domestic guinea pig(100731393) CD2-associated protein
- sheep(101117542) CD2-associated protein
- Domestic Rabbit(100341696) CD2-associated protein
- Zebrafish(494040) CD2-associated protein
- domestic cat(101091623) CD2-associated protein
- dog(474928) CD2-associated protein
- cow(533188) CD2-associated protein
- chicken(771715) CD2-associated protein
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