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Merck

CD1A

CD1a molecule

Synonyms:
CD1, FCB6, HTA1, R4, T6
Species:
Human CD1A (909), sheep CD1A (101111409), Domestic Rabbit CD1A (100037708), cow CD1A (782023), cow CD1A (781011), dog CD1A (610699)
UniProtKB ID:
P06126, D3DVD7, Q13962, Q5TDJ8, Q9UMM4, Q9Y5M5
Gene ID:
  • Human(909) Summary: This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
  • sheep(101111409) CD1a molecule
  • Domestic Rabbit(100037708) CD1a molecule
  • cow(782023) CD1a molecule
  • cow(781011) CD1a molecule
  • dog(610699) CD1a molecule

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